文字サイズ変更

業績

Achievements

患者様向け

2021年度

1.原著論文
No. 論文題名
1 Zonisamide improves axial symptoms in dementia with Lewy bodies with parkinsonism: Post hoc analysis of clinical trials/Tsuboi Y, Kochi K, Maruyama H, Matsumoto Y/eNeurologicalSci/2021 Dec 7;26:100384. doi: 10.1016/j.ensci.2021.100384. PMID: 34988303; PMCID: PMC8703232
2 Altered gut microbiota in Parkinson's disease patients with motor complications/Takahashi K, Nishiwaki H, Ito M, Iwaoka K, Takahashi K, Suzuki Y, Taguchi K, Yamahara K, Tsuboi Y, Kashihara K, Hirayama M, Ohno K, Maeda T/Parkinsonism Relat Disord. 2021 Dec 21;95:11-17. doi: 10.1016/j.parkreldis.2021.12.012. Epub ahead of print. PMID: 34954497
3 Zonisamide improves wearing off in Parkinson's disease without exacerbating dyskinesia: Post hoc analysis of phase 2 and phase 3 clinical trials/Tsuboi Y, Nakamura M, Maruyama H, Matsumoto Y/J Neurol Sci. 2021 Nov 15;430:120026. doi: 10.1016/j.jns.2021.120026. Epub 2021 Oct 7. PMID: 34715471
4 Intestinal Collinsella may mitigate infection and exacerbation of COVID-19 by producing ursodeoxycholate/Hirayama M, Nishiwaki H, Hamaguchi T, Ito M, Ueyama J, Maeda T, Kashihara K, Tsuboi Y, Ohno K/PLoS One. 2021 Nov 23;16(11):e0260451. doi: 10.1371/journal.pone.0260451. PMID: 34813629; PMCID: PMC8610263
5 Influence of istradefylline on non-motor symptoms of Parkinson's disease: A subanalysis of a 1-year observational study in Japan (J-FIRST)/Shimo Y, Maeda T, Chiu SW, Yamaguchi T, Kashihara K, Tsuboi Y, Nomoto M, Hattori N, Watanabe H, Saiki H; J-FIRST Group/Parkinsonism Relat Disord. 2021 Sep 21;91:115-120. doi: 10.1016/j.parkreldis.2021.09.015. Epub ahead of print. PMID: 34583302
6 Effects of safinamide adjunct therapy on pain in patients with Parkinson's disease: Post hoc analysis of a Japanese phase 2/3 study/Tsuboi Y, Koebis M, Kogo Y, Ishida T, Suzuki I, Nomoto M, Hattori N/J Neurol Sci. 2021 Oct 15;429:118070. doi: 10.1016/j.jns.2021.118070. Epub 2021 Sep 4. PMID: 34509801
7 Non-motor predictors of 36-month quality of life after subthalamic stimulation in Parkinson disease/Jost ST, Visser-Vandewalle V, Rizos A, Loehrer PA, Silverdale M, Evans J, Samuel M, Petry-Schmelzer JN, Sauerbier A, Gronostay A, Barbe MT, Fink GR, Ashkan K, Antonini A, Martinez-Martin P, Chaudhuri KR, Timmermann L, Dafsari HS; EUROPAR and the International Parkinson and Movement Disorders Society Non-Motor Parkinson’s Disease Study Group/NPJ Parkinsons Dis. 2021 Jun 8;7(1):48. doi: 10.1038/s41531-021-00174-x. PMID: 34103534; PMCID: PMC8187358
8 Cross-sectional analysis of the Parkinson's disease Non-motor International Longitudinal Study baseline non-motor characteristics, geographical distribution and impact on quality of life/van Wamelen DJ, Sauerbier A, Leta V, Rodriguez-Blazquez C, Falup-Pecurariu C, Rodriguez-Violante M, Rizos A, Tsuboi Y, Metta V, Bhidayasiri R, Bhattacharya K, Borgohain R, Prashanth LK, Rosales R, Lewis S, Fung V, Behari M, Goyal V, Kishore A, Lloret SP, Martinez-Martin P, Chaudhuri KR/Sci Rep. 2021 May 5;11(1):9611. doi: 10.1038/s41598-021-88651-4. PMID: 33953218; PMCID: PMC8100281
9 Long-term safety and efficacy of opicapone in Japanese Parkinson's patients with motor fluctuations/Takeda A, Takahashi R, Tsuboi Y, Nomoto M, Maeda T, Nishimura A, Yoshida K, Hattori N/J Neural Transm (Vienna). 2021 Mar;128(3):337-344. doi: 10.1007/s00702-021-02315-1. Epub 2021 Feb 25. PMID: 33630140; PMCID: PMC7969548
10 Randomized, Controlled Study of Opicapone in Japanese Parkinson's Patients with Motor Fluctuations/Takeda A, Takahashi R, Tsuboi Y, Nomoto M, Maeda T, Nishimura A, Yoshida K, Hattori N/Mov Disord. 2021 Feb;36(2):415-423. doi: 10.1002/mds.28322. Epub 2020 Oct 19. PMID: 33073879; PMCID: PMC7983910
11 The development of new method to differentiate between Dementia with Lewy bodies and Alzheimer's disease by cerebral perfusion SPECT-comparison to CIScore/Honda G, Nagamachi S, Nonokuma M, Takano K, Kuwabara Y, Yoshimitsu K, Iida H, Ogomori K, Kawasaki H, Tsuboi Y/Jpn J Radiol. 2021 Feb;39(2):198-205. doi: 10.1007/s11604-020-01041-0. Epub 2020 Sep 16. PMID: 32939741
12 DCTN1 Binds to TDP-43 and Regulates TDP-43 Aggregation/Deshimaru M, Kinoshita-Kawada M, Kubota K, Watanabe T, Tanaka Y, Hirano S, Ishidate F, Hiramoto M, Ishikawa M, Uehara Y, Okano H, Hirose S, Fujioka S, Iwasaki K, Yuasa-Kawada J, Mishima T, Tsuboi Y(corresponding author)/International Journal of Molecular Science. 2021;22(8):3985
13 A novel diagnostic marker for progressive supranuclear palsy targeting atrophy of the subthalamic nucleus/Fujioka S, Morishita T, Takano K, Takahashi N, Kurihara K, Nishida A, Mishima T, Suenaga M, Matsunaga Y, Tsuboi Y(corresponding author)/Journal of the Neurological Science. 2021;423:117366
14 Impact of Progression of Parkinson's Disease on Swallowing Ability and Oral Environment/Umemoto G, Fujioka S, Iwasa Y, Ozaki Y, Koga K, Nishimura K, Tsuboi Y/Parkinsons Disease. 2021;2021:5571556
15 The impact of tube replacement timing during LCIG therapy on PEG-J associated adverse events: a retrospective multicenter observational study/Yamashita K, Yube Y, Yamazaki Y, Fukuchi T, Kato M, Koike T, Uehara T, Ikeda Y, Furune S, Murakami H, Kubota E, Fujioka S, Sato Y, Jin X, Suzuki T, Furukawa K, Tsuboi Y/BMC Neurology. 2021;21(1):242
16 Longitudinal Changes of Tongue Thickness and Tongue Pressure in Neuromuscular Disorders/Umemoto G, Fujioka S, Arahata H, Sakae N, Sasagasako N, Toda M, Furuya H, Tsuboi Y/BMC Neurol. 2021;21(1):302
17 Leg Muscle Strength Correlates with Gait Performance in Advanced Parkinson Disease/Yokote A, Hayashi Y, Yanamoto S, Fujioka S, Higa K, Tsuboi Y(corresponding author)/Internal Medicine. 2021 Aug 13
18 Behavioral profile in a Dctn1G71A knock-in mouse model of Perry disease/Deshimaru M, Mishima T, Watanabe T, Kubota K, Hosoi M, Kinoshita-Kawada M, Yuasa-Kawada J, Ikeda M, Mori M, Murata Y, Abe T, Enjoji M, Kiyonari H, Kodama S, Fujioka S, Iwasaki K, Tsuboi Y(corresponding author)/Neuroscience Letter. 2021 Sep 8;764:136234
19 Off Time Independently Affects Quality of Life in Advanced Parkinson's Disease (APD) Patients but Not in Non-APD Patients: Results from the Self-Reported Japanese Quality-of-Life Survey of Parkinson's Disease (JAQPAD) Study/Hayashi Y, Nakagawa R, Ishido M, Yoshinaga Y, Watanabe J, Kurihara K, Nagaki K, Ogura H, Mishima T, Fujioka S, Tsuboi Y(corresponding author)/Parkinsons Disease. 2021;2021:9917539
20 Circulatory 25(OH)D and 1,25(OH)2D as differential biomarkers between multiple system atrophy and Parkinson's disease patients/Ogura H, Hatip-Al-Khatib I, Suenaga M, Hatip FB, Mishima T, Fujioka S, Ouma S, Matsunaga Y, Tsuboi Y/eNeurologicalSci. 2021;25:100369
21 Fluctuating pain in Parkinson's disease: Its prevalence and impact on quality of life/Kurihara K, Fujioka S, Kawazoe M, Mishima T, Ouma S, Tsuboi Y(corresponding author)/eNeurologicalSci. 2021;25:100371
22 Evaluation of Motor Complications in Parkinson's Disease: Understanding the Perception Gap between Patients and Physicians/Ogura H, Nakagawa R, Ishido M, Yoshinaga Y, Watanabe J, Kurihara K, Hayashi Y, Nagaki K, Mishima T, Fujioka S, Tsuboi Y(corresponding author)/Parkinsons Disease. 2021;2021:1599477
23 PLA2G6 variants associated with the number of affected alleles in Parkinson's disease in Japan/Daida K, Nishioka K, Li Y, Yoshino H, Shimada T, Dougu N, Nakatsuji Y, Ohara S, Hashimoto T, Okiyama R, Yokochi F, Suzuki C, Tomiyama M, Kimura K, Ueda N, Tanaka F, Yamada H, Fujioka S, Tsuboi Y, Uozumi T, Takei T, Matsuzaki S, Shibasaki M, Kashihara K, Kurisaki R, Yamashita T, Fujita N, Hirata Y, Ii Y, Wada C, Eura N, Sugie K, Higuchi Y, Kojima F, Imai H, Noda K, Shimo Y, Funayama M, Hattori N/Neurobiol Aging. 2021;97:147.e1-147.e9
24 Attitudes toward telemedicine of patients with Parkinson’s disease during the COVID-19 pandemic/Kurihara K, Nakagawa K, Inoue K, Yamamoto S, Mishima T, Fujioka S, Ouma S, Tsuboi, Y(corresponding author)/Neurol Clin Neurosci. (2021, 9: 77-82)
25 Meta-iodobenzylguanidine myocardial scintigraphy in Perry disease/Mishima T, Fujioka S, Nishioka K, Li Y, Sato K, Houzen H, Yabe I, Shiomi K, Eriguchi M, Hara H, Hattori N, Tsuboi Y(corresponding author)/Parkinsonism & Related Disorders. 2021;83:49-53
26 Proposed definition for young-onset ischemic stroke according to its cause. Clinical neurology and neurosurgery/Takeshita S, Ogata T, Arima H, Tsuboi Y(corresponding author)/2021;204:106595
27 Association of carotid ultrasonography with perioperative stroke after thoracic aortic aneurysm treatment: a retrospective study/Ito M, Shimada H, Ogata T, Hiromitsu T, Tsuboi Y, Inoue T, Wada H/Journal of medical ultrasonics. 2021;48:307-13
28 Quantification of Carotid Plaque Histology Using iPlaque Software/Ogata T, Shimada H, Inoue T, Takeshita S, Tsuboi Y, Uesugi N, Fujiwara M, Sata M, Yamada H/Ultrasound in medicine & biology. 2021
29 King’s Pakinson’s Disease Pain Scale(KPPS)とKing’s Pakinson’s Disease Pain Questionnaire(KPPQ)の日本語版の作成と言語的妥当性の検討/栗原可南子、藤岡伸助、三嶋崇靖、今野卓哉、関守信、坪井義夫(corresponding author)/臨床神経学. 2022 Jan 28;62(1):15-21
30 脳神経内科医におけるバーンアウト(第2報) 男性医師と女性医師の比較/久保真人、饗場郁子、下畑享良、服部信孝、吉田一人、海野佳子、横山和正、小川 崇、加世田 ゆみ子、小池亮子、清水優子、坪井義夫、道勇 学、三澤園子、宮地隆史、戸田達史、武田 篤/臨床神経学 2021; 61: 219-227
31 脳神経内科医におけるバーンアウトの現状と対策(第1報)/下畑享良、久保真人、饗場郁子、服部信孝、吉田一人、海野佳子、横山和正、小川崇、加世田ゆみ子、小池亮子、清水優子、坪井義夫、道勇 学、三澤園子、宮地隆史、戸田達史、武田 篤、日本神経学会キャリア形成促進委員会/臨床神経学; 61: 89-102
32 Effect of Robot-assisted Rehabilitation to Botulinum Toxin A Injection for Upper Limb Disability in Patients with Chronic Stroke: A Case Series and Systematic Review/Hyakutake K, Morishita T, Saita K, Ogata T et al/Neurologia medico-chirurgica. 2021
33 Factors Predictive of Enlargement of Dissecting Aneurysms in the Vertebral Artery/Horio Y, Ogata T (corresponding author), Abe H, et al/World neurosurgery. 2021;151:e935-e42. IF 2.104
34 Detection and Differentiation of Dural Arteriovenous Fistulas in the Transverse Sinus/Sigmoid Sinus and Cavernous Sinus Using Carotid Ultrasound: Importance of Evaluation of the Occipital Artery/Hisaeda E, Shimada H, Ogata T (corresponding author), Fukuda K, Higashi T, Inoue T/Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine. 2021;40:683-7
35 Neuroanatomical considerations for optimizing thalamic deep brain stimulation in Tourette syndrome/Morishita T, Sakai Y, Iida H, Yoshimura S, Ishii A, Fujioka S, Tanaka SC, Inoue T/Journal of Neurosurgery. 2021:1-11
36 経口コリンエステラーゼ阻害薬からリバスチグミンパッチ(イクセロンパッチ)に切り替えた市販後臨床試験(NEXTSTEP study)における事後解析/上田 兼吾、清瀬 一貴、鳥山 和宏、Shekhawat Ankita、新井 哲明、池邊 紳一郎、石田 義則、合馬 慎二、片山 禎夫、金谷 潔史、川瀬 裕士、櫻井 博文、島野 嵩久、杉谷 雅人、高橋 牧郎、田中 稔久、角 徳文、古田 伸夫、涌谷 陽介、中村 祐;Geriatric Medicine;59巻5号 2021.5
37 Encephalitis with Autoantibodies against the Glutamate Kainate Receptors GluK2/Landa J, Guasp M, Míguez-Cabello F, Guimarães J, Mishima T, Oda F, Zipp F, Krajinovic V, Fuhr P, Honnorat J, Titulaer M, Simabukuro M, Planagumà J, Martínez-Hernández E, Armangué T, Saiz A, Gasull X, Soto D, Graus F, Sabater L, Dalmau J/Ann Neurol. 2021, 90: 101-117
2. 症例報告
No. 論文題名
1 A refractory human T-cell leukemia virus type 1-associated myelopathy/tropical spastic paraparesis patient with lymphoma-type adult T-cell leukemia/lymphoma: A case report and review of the literature/Tamaki K, Mera H, Takeshita S, Fujioka S, Goto M, Matsumoto T, Yamano Y, Takamatsu Y, Tsuboi Y(corresponding author)/Medicine (Baltimore). 2021;100:e27450
2 Diphasic dyskinesia,すくみ足に対するレボドパ・カルビドパ経腸用液療法の至適用量:症例報告と文献的考察/岡島幹篤、藤岡伸助、籠田早織、西田明弘、三嶋崇靖、坪井義夫(corresponding author)/臨床神経学 (2021, 61: 398-400)
3 Case Report: GPi DBS for Non-parkinsonian Midline Tremor: A Normative Connectomic Comparison to a Failed Thalamic DBS/Morishita T, Sakai Y, Mishima T, Umemoto G, Okun MS, Tanaka SC, Tsuboi Y(7番目), Inoue T/Front Hum Neurosci. (2021, 15:709552)
4 Eosinophilic Granulomatosis with Polyangiitis Presenting with Myocarditis as an Initial Symptom: A Case Report and Review of the Literature/Kanako Kurihara, Jun Tsugawa, Shinji Ouma, Toshiyasu Ogata, Mikiko Aoki, Masatoshi Omoto, Takashi Kanda, and Yoshio Tsuboi(corresponding author)/Case Reo Neurol 2021 Jun10
5 原発性シェーグレン症候群に合併した免疫介在性壊死性ミオパチーの1例/髙橋信敬、西田明弘、津川潤、岡島幹篤、藤岡伸助、坪井義夫(corresponding author)/BRAIN and NERVE. 2021;73:183-187
ガンシクロビル耐性サイトメガロウイルス感染症の重篤化を回避した神経サルコイドーシス患者の1例/岩崎 清子、安高 勇気、松崎 翔平、竹下 翔、藤岡 伸助、坪井 義夫、神村 英利/日本病院薬剤師会雑誌 2021; 57: 1107-1112
前立腺癌増悪時に出現した傍腫瘍性オプソクローヌス、小脳性運動失調の1例/栗原可南子、福原康介、柳本祥三郎、津川 潤、坪井義夫(corresponding author)/BRAIN and NERVE: 神経研究の進歩 2021; 73: 179-182
Radiofrequency Ventro-oral Thalamotomy for Post-stroke Focal Dystonia in a Pediatric Patient/Hirao N, Morishita T, Saita K, Takagi T, Fujioka S, Inoue T/NMC Case Rep J. 2021;8:445-50